Diphenhydramine HCl 50 mg 029749515000

Diphenhydramine Hydrochloride Injection, USP 50 mg/mL is a sterile, nonpyrogenic solution intended for intramuscular or intravenous administration. Each 1 mL single-dose vial contains 50 mg of diphenhydramine HCl in water for injection, adjusted to a pH of 4.0–6.5 using sodium hydroxide or hydrochloric acid. This formulation is a generic equivalent to Benadryl®, offering high-potency antihistaminic relief in acute care settings.

Clinicians rely on diphenhydramine injection for rapid intervention in allergic reactions, anaphylaxis (as an adjunct to epinephrine), motion sickness, and mild cases of parkinsonism when oral therapy is impractical. Its anticholinergic and sedative properties make it a versatile agent in emergency and procedural environments.

This product is supplied in a box of 25 single-dose vials, making it ideal for hospitals, urgent care centers, medspas, and outpatient clinics. It is not intended for subcutaneous or intradermal use, and should never be used as a local anesthetic due to the risk of tissue necrosis.

Manufactured under strict quality standards, this injectable solution is latex-free, ensuring safety for patients with latex sensitivities. It should be stored at USP Controlled Room Temperature (20–25°C) and protected from light until use.

Diphenhydramine HCl injection is contraindicated in neonates, premature infants, and nursing mothers. Caution is advised in elderly patients and those with cardiovascular, respiratory, or neurological conditions. Adverse reactions may include drowsiness, dizziness, dry mouth, hypotension, and excitation in pediatric patients.