Qwo®

Do not receive QWO if you:
• Are allergic to any collagenase or to any of the ingredients in QWO. See the end of this Patient Information for a
complete list of ingredients in QWO.
• Have an active infection in the treatment area.

Before receiving QWO, tell your healthcare provider about all of your medical conditions, including if you:
• have had an allergic reaction to a QWO injection in the past
• have a bleeding problem
• are pregnant or plan to become pregnant. It is not known if QWO will harm your unborn baby.
• are breastfeeding or plan to breastfeed. It is not known if QWO passes into your breast milk. Talk to your
healthcare provider about the best way to feed your baby if you receive QWO.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines,
vitamins, and herbal supplements. Especially tell your healthcare provider if you take a medicine that prevents the
clotting of your blood (antiplatelet or anticoagulant medicine).

How will I receive QWO?
• QWO is injected into the fat (subcutaneously) of each single buttock (treatment area) by your healthcare provider. You
may receive up to 12 injections per treatment area.
• Each treatment visit may include up to 2 treatment areas.
• QWO injections will be given 21 days apart for 3 treatment visits

What are the possible side effects of QWO?
QWO may cause serious side effects, including:
• Allergic (hypersensitivity) reactions, including anaphylaxis. Call your healthcare provider right away if you have
any of these symptoms of an allergic reaction after an injection of QWO:
o hives o swollen face
o trouble breathing o chest pain
o low blood pressure o dizziness or fainting
• Injection site bruising.
The most common side effects of QWO include bruising, pain, areas of hardness, itching, redness, discoloration,
swelling and warmth in the treatment area.
These are not all of the possible side effects of QWO.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

General information about QWO
Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. If you would like
more information, talk to your healthcare provider. You can ask your pharmacist or healthcare provider for more
information about QWO that is written for health professionals.

What are the ingredients in QWO?
Active ingredient: collagenase clostridium histolyticum
Inactive ingredients: mannitol, sucrose, tromethamine, and hydrochloric acid
The diluent contains: calcium chloride dihydrate, sodium chloride, and Water for Injection, USP