Sold By: Merz Aesthetics
Rejuvenating Growth Factor and Peptide Treatment

Time is precious. Make it count with the only Human Growth Factors + Proprietary Peptides anti-aging formulation with proven results in less than a week. Minimize the appearance of fine lines and wrinkles, refines texture, brightens skin tone, improves firmness and elasticity, and boosts hydration as soon as 6 days.


Non-comedogenic • Dermatologist tested • Free of color additives and fragrances • Not tested on animals.


30 ml (1.0 fl oz)

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Key Benefits

  • Restore with Proprietary Peptides

  • Supports Collagen and Elastin production
  • Improves firmness, elasticity, tone, and texture
  • Rejuvenate with Human Growth Factors

  • Diminishes the appearance of fine lines and wrinkles
  • Redefines the look of facial contours
  • Hydrate with combination formulation

  • Increases skin hydration for enhanced skin smoothness and luminosity
  • Plumps up the appearance of skin
  • Fast results by Day 6

  • Smoother, tighter, firmer, and more hydrated skin (patient response)
  • Improved texture and brighter skin (clinical grader assessment)
  • Continued improvements at Week 8 (% of patients)

  • Texture (94%)
  • Brightness (92%)
  • Smoothness (88%)
  • Fine lines and wrinkles (eyes, mouth) (77%)


  • Apply in the morning and/or evening to the face, neck and décolleté, or as directed by your skincare professional.
  • For best results, use together with other NEOCUTIS anti-aging products.

Daily Ritual

  1. Begin with a daily cleanser.
  2. Apply BIO SERUM FIRM to address complex signs of aging in your skin.
  3. Add a facial moisturizer such as JOURNEE or MICRO DAY  in the morning and BIO CREAM or MICRO NIGHT in the evening.

Demonstrated Benefits Powered by NEOCUTIS Growth Factors & Proprietary Peptides

Unretouched photos of actual study subjects. Results based on a study of  subjects who applied BIO SERUM FIRM twice daily for 8 weeks. Results may vary. Date on file; Merz North America, Inc., Raleigh, NC. 

Key Ingredients

Human Growth Factors (anti-aging; supports Collagen and Hyaluronic Acid production)

Proprietary Peptides (boosts production of Collagen and Elastin)

Sodium Hyaluronate (increases skin elasticity; seals in moisture)

Arginine (antioxidant)

Glycerin (moisture-infusing)

Acetyl Glucosamine (skin-brightening; exfoliating)

Glutamine (supports Collagen production)

Pullulan (skin-tightening)

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Vendor Information

  • Store Name: Merz Aesthetics
  • Address: 6501 Six Forks Road
    Raleigh, NC 27615
    United States (US)
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